Cover Image

Thermodynamics of Pharmaceutical Systems

Published Online: 27 Feb 2003

Author(s): Kenneth A. Connors

Print ISBN: 9780471202417    Online ISBN: 9780471234920

DOI: 10.1002/0471234923

Copyright © 2002 John Wiley & Sons, Inc.

thermodynamics_pharmac_2003.pdf

 

“…eminently suitable for its target audience…the book will also be of use to anyone in the pharmaceutical field who has forgotten his or her thermo and needs a refresher course…” (Pharmaceutical Development and Technology, Vol. 8, No. 3)

“…the book for those who are just entering the world of thermodynamics as well as for those…without active participation…this book should be the one to read first before any other books…graduate students…and those scientists in pharmaceutical industry will find the book…invaluable in their research…” (Pharmaceutical Research, Vol. 20, No. 9, September 2003)

PREFACE.

I: BASIC THERMODYNAMICS.

1. Energy and the First Law of Thermodynamics.

1.1. Fundamental Concepts.

1.2. The First Law of Thermodynamics.

1.3. The Enthalpy.

2. The Entropy Concept.

2.1. The Entropy Defined.

2.2. The Second Law of Thermodynamics.

2.3. Applications of the Entropy Concept.

3. The Free Energy.

3.1. Properties of the Free Energy.

3.2. The Chemical Potential.

4. Equilibrium.

4.1. Conditions for Equilibrium.

4.2. Physical Processes.

4.3. Chemical Equilibrium.

II: THERMODYNAMICS OF PHYSICAL PROCESSES.

5. Introduction to Physical Processes.

5.1. Scope.

5.2. Concentration Scales.

5.3. Standard States.

6. Phase Transformations.

6.1. Pure Substances.

6.2. Multicomponent Systems.

7. Solutions of Nonelectrolytes.

7.1. Ideal Solutions.

7.2. Nonideal Solutions.

7.3. Partitioning between Liquid Phases.

8. Solutions of Electrolytes.

8.1. Coulombic Interaction and Ionic Dissociation.

8.2. Mean Ionic Activity and Activity Coefficient.

8.3. The Debye-Hu¨ckel Theory.

9. Colligative Properties.

9.1. Boiling Point Elevation.

9.2. Freezing Point Depression.

9.3. Osmotic Pressure.

9.4. Isotonicity Calculations.

10. Solubility.

10.1. Solubility as an Equilibrium Constant.

10.2. The Ideal Solubility.

10.3. Temperature Dependence of the Solubility.

10.4. Solubility of Slightly Soluble Salts.

10.5. Solubilities of Nonelectrolytes: Further Issues.

11. Surfaces and Interfaces.

11.1. Thermodynamic Properties.

11.2. Adsorption.

III: THERMODYNAMICS OF CHEMICAL PROCESSES.

12. Acid-Base Equilibria.

12.1. Acid-Base Theory.

12.2. pH Dependence of Acid-Base Equilibria.

12.3. Calculation of Solution pH.

12.4. Acid-Base Titrations.

12.5. Aqueous Solubility of Weak Acids and Bases.

12.6. Nonaqueous Acid-Base Behavior.

12.7. Acid-Base Structure and Strength.

13. Electrical Work.

13.1. Introduction.

13.2. Oxidation-Reduction Reactions.

13.3. Electrochemical Cells.

13.4. pH Measurement.

13.5. Ion-Selective Membrane Electrodes.

14. Noncovalent Binding Equilibria.

14.1. Introduction.

14.2. The Noncovalent Interactions.

14.3. Binding Models.

14.4. Measurement of Binding Constants.

APPENDIXES.

A. Physical Constants.

B. Review of Mathematics.

B.1. Introduction.

B.2. Logarithms and Exponents.

B.3. Algebraic and Graphical Analysis.

B.4. Dealing with Change.

B.5. Statistical Treatment of Data.

B.6. Dimensions and Units.

ANSWERS TO PROBLEMS.

BIBLIOGRAPHY.

INDEX.

thermodynamics_pharmac_2003.pdf

2 comentarios en “Libro: THERMODYNAMICS OF PHARMACEUTICAL SYSTEMS

Puedes decir algo sobre la entrada actual…

Por favor, inicia sesión con uno de estos métodos para publicar tu comentario:

Logo de WordPress.com

Estás comentando usando tu cuenta de WordPress.com. Cerrar sesión / Cambiar )

Imagen de Twitter

Estás comentando usando tu cuenta de Twitter. Cerrar sesión / Cambiar )

Foto de Facebook

Estás comentando usando tu cuenta de Facebook. Cerrar sesión / Cambiar )

Google+ photo

Estás comentando usando tu cuenta de Google+. Cerrar sesión / Cambiar )

Conectando a %s